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It also improves the utilization of blood glucose (sugar), which aids in burning carbohydrates for energy rather than storing them as fat, increases leptin sensitivity, which causes your body to preferentially burn body fat for a longer period of time, and changes natural brain chemistry, which directly reduces appetite
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[1] The medication is not recommended during pregnancy, and women of childbearing potential should use effective contraception
Neither medication manages blood sugar or weight to the same degree as newer versions, but these older drugs are still good options for people with mild diabetes who are not overweight, says Sue Pedersen, an endocrinologist and obesity medicine specialist at the C-endo diabetes and endocrinology clinic in Alberta
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