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Although every patients condition has to be evaluated, generally, when treating a B12 deficiency, according to the University of Virginia report, its effective for your physician to start you with 1,000-microgram shots every day or two for the first week

Enzymes, pH fluctuations, and the liver's first-pass metabolism can all dramatically reduce the bioavailability of a compound

As for safety, tolerable upper intake levels (known as ULs) are set for vitamins and minerals when evidence is sufficient

Warnings & Storage WARNING: If you are pregnant, nursing, taking any medications, or have any medical conditions, consult your doctor before use