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The diagnostic algorithm is first based on evidence of immune-mediated destruction based on two or more of the following: 1) Moderate to many spherocytes (dogs only), 2) Positive saline agglutination tests without washing, and 3) Detection of RBC-bound immunoglobulin or complement with Coombs or flow cytometric testing or a persistent positive saline agglutination test after washing RBCs
Therefore, the most reliable diagnostic tool is a food elimination trial combined with symptom tracking
Also called beetroot red, betanin is the most common pigment in beetroots, responsible for their strong red color
