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Although most guidelines continue to recommend metformin as first-line anti-hyperglycemic therapy, the European Society of Cardiology [52] recommends that GLP-1RA or SGLT2i should be first-line therapy in individuals with ASCVD or at high or very high CV risk
Constipation may shift to diarrhea, or alternate between the two
And that's something to be incredibly proud of
In addition, whether early initiation of GLP-1RA in patients with newly diagnosed T1D can preserve cell function remains to be determined in large RCTs
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