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In addition, we describe an epigenetic compensatory system, comprised of bromodomain-containing protein 4 (BRD4) and microRNA-29, that may counteract ferroptosis by activating cystine/glutamate antiporter, while lowering ferritin autophagy and iron regulatory protein-2
Kecel-Gunduza, S., Kocb, E., Bicaka, B., Kokcub, Y., Ozela, A
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3) Promotion of glutaminase 2 (GLS2) expression: GLS2 expression is induced in a p53-dependent manner in response to DNA damage or oxidative stress, and p53 is associated with the GLS2 promoter
They can affect hydration, medication timing, and the ability to keep regular meals down
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