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2024 Feb;78(2):155-162

Clin Pharmacokinet

P., Albeck, J

On June 10th, researchers from Eli Lilly published findings of a randomized phase 2a clinical trial in "Nature Medicine" titled Triple hormone receptor agonist retatrutide for metabolic dysfunction-associated steatotic liver disease: a randomized phase 2a trial. The study indicated that Retatrutide (LY3437943), a GLP-1R-related triple receptor agonist currently under clinical development, demonstrated significant efficacy and favorable safety in the treatment of metabolic dysfunction-associated steatotic liver disease (MASLD)