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They work by mimicking a natural hormone called GLP-1, which helps regulate blood sugar levels and appetite
When this balance is disrupted, cholesterol can precipitate out of solution and form crystals, which may aggregate into gallstones
The landmark FLOW trial demonstrated that semaglutide reduced the risk of significant kidney events by 24% compared to placebo in patients with type 2 diabetes and chronic kidney disease
doi:10.1111/dom.15113 50
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