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A slight blip might not mean much, but a consistent upward trend in creatinine or a downward trend in eGFR is what your healthcare provider will pay attention to
Yes, but it varies between individuals
This exclusivity blocks FDA acceptance of any ANDA or 505(b)(2) application for four years (creating the window for Paragraph IV challenges) and blocks FDA approval for five full years
(PubMed) Mayr JA, Zimmermann FA, Fauth C, et al
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