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This is noteworthy as these analogues are at least 10-fold less potent then GLP-1-G 2 ( 1 ), meaning that even if at least 10 times more compound is required to get the same activity in vitro, they have a significant longer acting period
Spring is an ideal time to refresh these routines as longer days and warmer weather encourage more outdoor activity and increased UV exposure
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This started with the launch of the long-acting/extended release exenatide microspheres, followed by dulaglutide and albiglutide in 2014.10 Interestingly, perhaps the most successful of this wave of once-weekly products, dulaglutide, was launched in a three-step autoinjector, which compared favourably with formulations that required more complicated preparation steps for the user
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