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The FDA label includes a boxed warning regarding thyroid C-cell tumors observed in rodent studies, contraindicating use in patients with personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2

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DSIP dosing protocols Establishing optimal DSIP dosing requires understanding that human research is limited compared to many other peptides

Injectable GHK-Cu was in Category 2 the more restrictive category for substances with "significant safety concerns." Its removal from Category 2 is the more positive development, as it signals the FDA no longer considers injectable GHK-Cu to carry the safety risk level that warranted Category 2 placement