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Presented for research literature review only von Eyben F et al
The primary causes of pulmonary embolism involve the formation of a blood clot, most frequently originating in the deep veins of the legs, a condition known as deep vein thrombosis (DVT)
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In this Review, we posit that eight molecular hallmarks are common denominators in cardiovascular ageing, namely disabled macroautophagy, loss of proteostasis, genomic instability (in particular, clonal haematopoiesis of indeterminate potential), epigenetic alterations, mitochondrial dysfunction, cell senescence, dysregulated neurohormonal signalling and inflammation
