can you take semaglutide with hrt Progress Hormone therapy may boost weight

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While this supports weight loss, it can also leave you feeling low on energy

In 2025, the American Association of Clinical Endocrinology updated its Obesity Algorithm, which highlights the importance of preserving skeletal muscle during medical weight-loss interventions: patients who retain strength tend to experience fewer side effects, more energy, and better long-term weight maintenance

[1] Other documented side effects include injection site reactions, fatigue, hypoglycemia (particularly when used with insulin or insulin secretagogues), and increased heart rate