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Dosing flexibility Wegovy follows a fixed dose escalation schedule, typically progressing to the maintenance dose of 2.4 mg over 16-20 weeks
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51,52 Although our preclinical studies mostly employed male mice, this choice was made to minimize variability, particularly because MAOB is located on the X chromosome, making males a more straightforward model for assessing MAOB effects without the potential confound of X-inactivation
Alves G, Lange J, Blennow K, Zetterberg H, Andreasson U, Frland MG, et al
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