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When symptoms occur, they usually relate to underlying conditionssuch as liver disease, kidney dysfunction, or haematological disordersthat cause the elevation
11 Our study results were similar to those of Zubair et al, 14 who reported that, similar to the results obtained for the placebo group, after 12 injections of glutathione over six weeks, only six (37.5%) participants experienced skin tone improvement of at least one level
Finally, we propose future directions including personalized nutraceutical strategies, AI-assisted discovery, and global regulatory harmonization positioning nutraceuticals as sustainable and evidence-based adjuncts or alternatives in chronic disease management
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