Yes, rapid improvement in glycemic control with any diabetes medication can occasionally trigger treatment-induced neuropathy of diabetes, which presents as acute painful neuropathy and typically improves over time
Drug Interactions You should not take bupropion if you are on other bupropion-containing products (Contrave, Wellbutrin, Aplenzin) or are currently taking Monoamine Oxidase Inhibitors (Marplan, Nardil, Emsam, Parnate)
Tirzepatide (weekly injection) is a dual GIP/GLP-1 agonist that may produce even greater results
You can boost GLP-1 naturally by eating fiber-rich foods, healthy fats, lean proteins, exercising regularly, managing stress, and getting good sleep