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In the present study, we extend these findings by showing livers from GCLM KO mice exhibit a persistently greater level of oxidant stress as measured by protein carbonylation and expression of redox-sensitive genes

If the cause of your lack of vitamin B12 is diet related rather than due to pernicious anaemia then treatment may be different

In PD, disruptions to the BBB facilitate the spread of Syn within the brain, while Syn aggregates reciprocally worsen BBB damage by instigating immune reactions or compromising BBB integrity, perpetuating a detrimental feedback loop that accelerates PD's pathology

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