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The pathogenic mechanism of OA include damage to periarticular cartilage and subchondral bone, synovitis, and the critical involvement of chondrocytes in this process
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It might boost the effect of these drugs and lead to hypoglycemia (low blood sugar)
Theoretically, combining AOD-9604 with beta-3 agonists (mirabegron) could amplify lipolytic effects, though no clinical reports describe this interaction
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