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The trial included a 24-week extension period at doses of 9 or 12 mg for about 500 adults with a BMI of 35 or greater, which is classified as severe obesity

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This article primarily reviews the main signaling pathways and regulatory factors involved in regulating ferroptosis, the role of ferroptosis in renal fibrosis, and potential therapeutic strategies that interfere with ferroptosis in the treatment of renal fibrosis

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