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XL413, an inhibitor of CDC7 kinase, effectively induced senescence in liver cancer cells, simultaneously sensitizing them to the senolytic action of the mTOR inhibitor, AZD8055 [136]
Every injectable medication carries some risk of injection site reactions
CONCLUSIONS CONFLICTS OF INTEREST In the last 5 years Adie Viljoen has received lecture honoraria and/or travel support and/or conducts clinical trials funded by: Amarin, Amgen, Astra Zeneca, Boehringer Ingleheim, Daiichi-Sankyo, Lilly, Menarini, NewAmsterdam, Novartis, Novo Nordisk, Pfizer, Regeneron, Sanofi, Takeda, and Tosoh
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