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Overall, these studies suggest that chronic stress or unhealthy diets can lead to morphological and pro-inflammatory changes in enteric glia, leading to intestinal inflammation, gut dysbiosis, and reduced structural and functional integrity of the ENS

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The DNA sequence spanning the CBS gene ARE motif located 4970 bp upstream of the transcript start site and its mutants were cloned into a GFP expressing reporter pEGFP-N1 (PT3054, Clontech) with sequence specific primers (Supplementary Table 1)

From the picture, the hypothesis framework is accepted because the correlation is negative