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Thats because GLP-1s may cause GI side effects, such as vomiting and diarrhea, that can contribute to dehydration
In December 2025, Eli Lilly submitted the drug to the FDA for weight loss and plans to submit it for type 2 diabetes in 2026
At the same time, it exhibits a favorable safety profile in animal studies
Recent research suggests that high-concentration protein systems can leverage self-buffering to improve stability and patient comfort, potentially bypassing patents that require specific citrate or phosphate buffers
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