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Do not overlap injections to avoid adverse reactions
Several commercial weight loss clinics offer B12 injections as part of their programmes, but these are not evidence-based treatments, and any perceived benefit is likely attributable to other concurrent lifestyle changes
"Tirzepatide Once Weekly for the Treatment of Obesity." NEJM 2022 (SURMOUNT-1) ClinicalTrials.gov: TRIUMPH Phase 3 program trial protocols and status updates FDA Prescribing Information: Wegovy, Mounjaro/Zepbound, Saxenda (for comparative safety data) Frequently Asked Questions Most side effects peak during dose escalation (weeks 412) and improve substantially by week 24
Joint or muscle pain can occur, but severe or limiting pain should be reported
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