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However, native GLP-1 has a very short half-life only about 12 minutes because it is rapidly degraded by the enzyme DPP-4 (dipeptidyl peptidase-4)
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When fluid intake is low, stool can become harder and move more slowly through the intestines, increasing the likelihood of constipation while taking tirzepatide
In elderly patients with dysthymic disorder, it was found comparable to fluoxetine (45) , but ineffective against Alzheimers disease (46) (47)
Because older people generally have greater cardiovascular risk than younger people, their risk of NSAID-related cardiovascular events may also be elevated
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