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His clinical journey aligns with evidence from pivotal GLP-1 studiessuch as those in the LEAD series for liraglutideand reinforces the value of integrative management strategies, which include medication titration, lifestyle modification, and vigilant follow-up (16)
10.1016/j.chroma.2008.08.023 118 MiyasakaS
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To counter the reduction in insulin sensitivity of the -cells, supraphysiological doses of GLP1-RA (as in GLP1-RA therapy) partially restore the incretin effect
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