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Priority research needs include large-scale randomized controlled trials to establish efficacy and safety, dose-ranging studies to optimize treatment protocols, long-term safety studies particularly regarding cancer risk, and comparative effectiveness research with established therapies

Glutathione, the primary antioxidant that our body produces naturally, plays a crucial role in preventing aging, cancer, cardiovascular diseases, dementia, and many other illnesses

For example, a patient with biopsyproven celiac disease who remains symptomatic despite strict gluten avoidance and has objective markers of increased permeability might eventually be a candidate for a regulated larazotidebased therapy, if and when such products are approved

Every systemic finding comes from animal models or cell culture