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Carrier-free nanoassembly of doxorubicin prodrug and sirna for combinationally inducing immunogenic cell death and reversing immunosuppression
[7] [9] These contraindications are based on known metabolic pathways, clinical case reports, and established pharmacological principles, and are supported by clinical guidelines and expert consensus
It is, however, possible to reduce metal toxicity risk through lifestyle choices that diminish the probability of harmful heavy metal uptake, such as dietary measures that may promote the safe metabolism or excretion of ingested heavy metals
Comparing the schistosomicidal activity against juvenile worms with that of PZQ reported in previous in vivo studies 61 , the inhibitors reported herein show superior schistosomicidal activity to PZQ at the worm developmental stage in mice
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