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B., Sard, F
It is also approved in the United States for the reduction of major adverse cardiovascular events such as death, heart attack, or stroke in adults with type 2 diabetes who have established cardiovascular disease or multiple cardiovascular risk factors
These combined effects make GLP-1 therapy a comprehensive tool for anyone looking to reduce the health risks associated with obesity and improve their long-term quality of life
It has a high affinity to GLP-1R, strongly activating the GLP-1R Gs cAMP pathway without inducing measurable -arrestin recruitment signaling, which indicates it is a fully biased agonist
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