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However, during high-intensity exercise, the rapid demand for energy causes carbohydrates to become the main energy substrate

This is the mechanism that supports its inclusion in Contrave (bupropion-naltrexone) as an FDA-approved weight loss combination

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[2] Iron supplements may cause a grayish-black stool that should be distinguished from melena, [3] as should black coloration caused by a number of medications, such as bismuth subsalicylate (the active ingredient in Pepto-Bismol), or by foods such as beetroot, black liquorice, or blueberries