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Where GLP-1 Medications Come In GLP-1 receptor agonists (like semaglutide and tirzepatide) work by: Slowing gastric emptying Increasing satiety Reducing appetite and food noise Improving insulin sensitivity For many perimenopausal women, this can feel like a reset of hunger signals that had become dysregulated

This is mainly due to the functioning of the pineal gland deteriorating with increased age and a reduction of hormone circadian rhythm amplitude

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While Medicare currently is prohibited by statute from covering weight-loss-only medications, the Center for Medicare and Medicaid Innovation has the authority to design and test new payment models that lower program spending while maintaining or improving the quality of care