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Fat oxidation is driven by caloric deficit, not methyl donors

10.1080/13543784.2023.228807338006580 8 Mitchell JL, Lyons HS, Walker JK, et al

Because its a stimulant, the phentermine label warns about increases in blood pressure, insomnia if taken late in the day, and its contraindicated in people with a history of cardiovascular disease, uncontrolled hypertension, hyperthyroidism, glaucoma, agitated states, or a history of drug abuse