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Its dual mechanism is one reason it produces larger average weight loss than single-target GLP-1 drugs like semaglutide in cross-trial comparisons
For instance, drugs that cause urinary retention or reduce bladder emptying can increase UTI risk by allowing bacteria to multiply in the urinary tract
It's a one-two punch that amplifies the natural signal significantly
This is why the TGA in Australia in 2008 granted the peptide the classification of safe supplementary substance, an exceptional regulatory step for a molecule that failed in its primary indication
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