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European Journal of Pharmacology, 869 , 172891
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Safety and Monitoring : Given the potential risks, especially related to tumor growth due to increased angiogenesis, it is crucial to monitor health metrics and use the minimum effective dose
Further, targeted metabolomics and isotope tracing experiments uncovered GGCT as a metabolic orchestrator to prioritize Gln to GSH flux for antioxidant defense, while activating glucose (Glc)-fueled anaplerosis to replenish TCA intermediates to fuel proliferation
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