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397,398 Minihepcidins are small engineered peptides that produce iron-limiting effects like the hepcidin hormone

The Sikiric group has consistently characterized BPC-157 as resistant to degradation in human gastric juice, a property attributed to its compact 15-residue length, its five proline residues (which disrupt protease recognition motifs), and the absence of cysteine-bridgedependent tertiary structure (Sikiric et al., 2018)

In this particular study, the researchers performed surgery on rats, removing a different organ from each rodent in an attempt to better understand which organ systems BPC-157 interacts with outside of the stomach