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Factors accelerating tolerance include consistent calorie restriction without adequate protein, insufficient water intake, sedentary behavior, and rapid dose escalation followed by long plateaus at a single dose
Patients with personal or family history of medullary thyroid carcinoma should not use these drugs
A functional stool test evaluates the abundance and diversity of beneficial bacteria in the gut, the "good guys" that promote health and keep pathogens in check
But the consistency across anecdotes suggests these options are worth exploring with medical guidance
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