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Red blood cells express a functional endothelial nitric oxide synthase
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The 4-phosphopantetheine group serves as the acyl carrier portion (ACP) of several lipid biosynthetic enzymes that includes cytosolic fatty acid synthase and the mitochondrial NDUFAB1 encoded protein (NADH:ubiquinone oxidoreductase subunit AB1) which serves as the ACP in mitochondrial fatty acid synthesis
The study also suggested that oxidative stress, a known trigger of eryptosis, may contribute to the membrane alterations observed in RBCs of LC patients
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