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Unlike these receptors, ligand recognition by TLR13 is sequence-specific, identifying a 13-nucleotide ssRNA sequence (5-XCGGAAAGACCXX-3) conserved in bacterial 23S ribosomal RNA and present in similar viral ssRNA sequences [21]
These properties make it a dual-action drug, addressing both glycemic control and weight management, which are often concurrent issues in patients with type 2 diabetes and obesity
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