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Evidence behind common 5-Amino-1MQ benefit claims Claimed outcome Fat-mass changes Evidence level Animal evidence What research currently shows Obese mouse studies reported less body-weight gain, lower fat mass, or smaller fat cells after NNMT inhibition

Mice from a different substrain and vendor, but fed similar lean and high-fat diets to this study, showed a predominance of the family Erysipelotrichaceae, of which Ileibacterium is a genus, in their cecal microbiomes 76

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Trial durations were relatively short, typically 12 weeks maximum