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Skipping days or frequently changing products often slows progress
The gradual dose titration schedule recommended in the prescribing information is specifically designed to minimize these gastrointestinal effects
It allows semaglutide levels to decrease enough that you are not getting double GLP-1 activation when tirzepatide begins
Retatrutide is an investigational triple agonist targeting GLP-1, GIP, and glucagon receptors, currently without UK marketing authorisation from the MHRA or EMA
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