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In addition, it is noteworthy that several foundational studies have reported alterations in microglial gene expression, plausibly reflecting DAM-like phenotypes, in both aging and AD models of mice and humans (Sierra et al., 2007
Likewise, excessive inactivity doesnt just come as a side effect of depression
Cells were selected if their UMI counts ranged from 200 to 50,000, the number of detected genes per cell fell within the 1090% range of total detected levels, and mitochondrial gene counts were below 10%
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