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: Off Label Pseudophakic patients with glaucoma (Schmidt et al 2010) A 2010 study (Schmidt et al, 2010) concluded that echothiophate may be effective in lowering IOP in patients with advanced glaucoma that have had previous cataract surgery to replace their eye's natural cloudy lens with a clear aritificial intraocular lens (pseudophakic patients), and for whom maximal medical therapy with newer class medications provides insufficient lowering of IOP
Additionally, many prescription medications can bring side effects that discourage long-term use
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two adjacent aspartic acid residues at positions 10 and 11 create a localized acidic region at physiological pH
