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They also might be prescribed lower dosages in clinical practice than were used in the drug trials
They can help weigh the pros and cons of each option to find the most appropriate one
However CMS specified they may also require prior authorizations to ensure that is being used only for the approved use
CYP3A4 inhibitors (e.g., itraconazole, ritonavir, cobicistat): These can inhibit the metabolism of corticosteroids, potentially increasing steroid levels and the risk of side effects
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