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In brain injury models, it reduced swelling and bleeding and improved recovery outcomes suggesting it may help preserve neurological function under stress
[12] Parenteral choline supports fetal neurodevelopment, yet the safety of supraphysiologic methyl-donor combinations in pregnancy lacks robust evidence
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The peptide also promotes polarization of macrophages from pro-inflammatory M1 phenotypes toward tissue-repairing M2 phenotypes, with treated macrophages showing 70% increased phagocytic activity for clearing inflammatory debris and 3-fold higher production of VEGF compared to untreated controls
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