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[3][16][17] In conditions such as obesity, type 2 diabetes, and aging, NNMT is overexpressed in adipose tissue and skeletal muscle, where it depletes cellular pools of NAD+ and SAM
[3] Sublingual and nasal preparations are available but are not routinely recommended within UK clinical guidance and may not be licensed as medicines
Protocols vary based on the condition being treated acute injuries typically involve a more intensive initial phase, followed by a maintenance dose
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