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One of the RCTs found significant mean improvements in Clinical Global Impressions-Improvement (CGI-I) score and cellular methylation capacity, but not in the Aberrant Behaviour Checklist (ABC), Social Responsiveness Scale (SRS) or GSH metabolism, with those who had the lowest methionine status at baseline (suggesting impaired methylation capacity) significantly more likely to respond to supplementation

Romanian journal of internal medicine = Revue roumaine de medecine interne

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The supplemented group showed elevated physiological selenium levels in their hair samples and exhibited a substantially lower prevalence of KBD 74