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In Trem2-deficient foamy macrophages, the cholesterol biosynthesis pathway cannot be downregulated, leading to impaired lipid uptake, increased mortality of foamy macrophages, inhibited clearance of apoptotic cells, and ultimately, the development of atherosclerosis (Patterson et al., 2023) (Figure 1)
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In a recent study, Wang et al
Available from: Dzaye O, Berning P, Razavi AC, Adhikari R, Jha K, Nasir K et al (2022) Online searches for SGLT-2 inhibitors and GLP-1 receptor agonists correlate with prescription rates in the United States: an infodemiological study
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