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Later, a Science investigation raised suspicions, presenting evidence that Sylvain Lesn, a professor in UMN's Department of Neurology, who was Ashe's protg and the paper's first author, used manipulated data not only in the Nature paper but in other publications as well

Hyperglycemia has been linked to oxidative stress in diabetes 36,37 , and it is possible that increased carbohydrates in Icelandic diets in the 19th century created enough oxidative stress in L68Q-hCC carriers to make presentation of the disease more severe

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