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The Phase 2 clinical data supports a threshold model
Breaking that down further: 86.4% lost at least 5% of body weight 69.1% lost at least 10% of body weight 50.5% lost at least 15% of body weight 32% lost 20% or more of body weight For a 200-pound person, 14.9% weight loss equals about 30 pounds, bringing them to 170 pounds
These blood tests can help determine if youre low on B12 (6)
If your medication has a warning not to eat grapefruit while taking it, you shouldnt take berberine with it, either.55 (Note, also, that berberine isnt the only supplement that interacts with cytochrome P450)
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