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Therefore, GLP-1R is considered a potential therapeutic target for diseases related to brain glucose metabolic disorders

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For example, botulinum neurotoxin is associated with a hemagglutinin complex or other protein complexes that either bind to specific receptors on the enterocyte luminal cell membrane or disrupt the junctional protein E-cadherin to open the paracellular spaces for the absorption of the toxin [83]

This prohibition extends to both in-competition and out-of-competition use across all sports under WADA jurisdiction