Contact your healthcare provider promptly if you experience: Persistent or severe gastrointestinal symptoms that interfere with nutrition or hydration Signs of dehydration (decreased urination, dizziness, dry mouth, dark urine) Unexplained abdominal pain, especially if severe or radiating to the back Yellowing of skin or eyes (jaundice) Symptoms of low blood sugar (shakiness, sweating, confusion, rapid heartbeat) New or worsening depression, suicidal thoughts, or unusual changes in mood or behavior Persistent lump or swelling in the neck, hoarseness, or difficulty swallowing For patients with diabetes: changes in vision or eye pain Seek immediate emergency medical attention (call 911) if you develop: Symptoms suggestive of blood clots (unilateral leg swelling with pain, sudden shortness of breath, chest pain) Severe allergic reactions (difficulty breathing, facial swelling, widespread rash) Severe, unrelenting abdominal pain with vomiting Signs of acute kidney injury (marked decrease in urination, severe swelling) Altered mental status or loss of consciousness Patients should never discontinue Zepbound abruptly without medical guidance, and any concerns about side effects should be discussed with the prescribing provider

GLP-1RAs did not affect Pulmonary hypertension (RR 1.02, 95% CI 0.512.05, p = 0.95
If you've already injected, monitor for side effects
A follow-up pilot study by Sinha et al