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Individual variation matters Clinical trial averages mask enormous individual variation
Combined with reduced food intake overall, these effects are compounding
DOI: 10.1038/s41467-020-20790-0 Frontiers in Physiology (2025) MOTS-c treatment restored mitochondrial respiration in type 2 diabetic hearts, improved fasted blood glucose, and improved glucose handling in T2D rat models, consistent with AMPK pathway activation and increased mitochondrial biogenesis markers
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